Welcome to the ultimate DeRose Health Ageless Review — your complete guide to one of today’s most advanced plant-based phytoceramide supplements.
Unlike typical topical creams that only work on the skin’s surface, DeRose Health Ageless II works from within, rebuilding your skin barrier, restoring moisture, enhancing firmness, and revitalizing hair and nails.
If you’re 35+, battling dryness, fine lines, dullness, thinning hair, or brittle nails, this supplement offers a clinically substantiated, clean-label solution that easily fits into your daily routine.
Why wait until the signs of aging deepen? Start your transformation now and give your skin and hair the nourishment they deserve — naturally.
| Feature | Description |
|---|---|
| Product Name | DeRose Health Ageless II Phytoceramide Supplement |
| Active Ingredient | Rice-derived phytoceramides (100mg per serving) |
| Additional Nutrients | Biotin (5000mcg), Vitamins A, C, D, E |
| Capsule Type | Vegetarian-friendly, plant-based cellulose capsule |
| Allergen Info | Free from gluten, soy, sugar, GMOs, artificial additives |
| Manufacturing | Made in FDA-registered, GMP-compliant facility |
| Suggested Use | 1 capsule daily |
| Target Audience | Adults (esp. 35+), men and women |
| Main Benefits | Boosts hydration, firmness, skin barrier, with hair & nail support |
| Satisfaction Guarantee | 90-day risk-free trial |
| Customer Rating | 4.6-star average rating |
How DeRose Health Ageless II Works: The Science in Action
Phytoceramides are lipids naturally found in your skin but decline significantly as you age — causing dryness, sagging, and hair fragility.
DeRose Health Ageless II delivers one of the highest phytoceramide doses on the market (100mg per serving), combined with biotin and antioxidant vitamins to:
- Rebuild your skin barrier to lock in long-lasting moisture
- Reduce water loss for plumper, more supple skin
- Support collagen & elastin integrity for firmness
- Strengthen hair follicles and nails
- Shield cells from oxidative stress caused by sun and pollution
Most users report a visible transformation within 3–6 weeks — including softer skin, improved elasticity, and a healthier scalp and hair.
DeRose Health Ageless vs Competitors
| Feature | DeRose Health Ageless II | CeramidePure | Life Extension Skin Restoring | PhytoRenew 350 |
|---|---|---|---|---|
| Phytoceramide Source | Rice-derived | Wheat-based | Rice-derived | Synthetic blend |
| Phytoceramide Dose | 100mg | 40mg | 30mg | 350mg (blend) |
| Biotin | 5,000mcg | None | 300mcg | 500mcg |
| Vitamins Included | A, C, D, E | None | Vitamin D only | None |
| Clean Label | Yes | Yes | No | Yes |
| Vegetarian Capsule | Yes | No (gelatin) | Yes | Yes |
| Gluten/Soy/Sugar Free | Yes | No | No | Yes |
| GMP/FDA Certified | Yes | No | Yes | No |
| Satisfaction Guarantee | 90 days | 30 days | 30 days | 30 days |
| Customer Rating | 4.6 stars | 4.2 stars | 4.0 stars | 4.1 stars |
Pros and Cons
Pros
- High-potency 100mg rice-derived phytoceramides per serving
- Fortified with biotin & antioxidant vitamins for multi-benefit support
- Clean-label — no gluten, soy, GMOs, sugar, or artificial additives
- Vegetarian-friendly capsules
- Made in the USA in FDA-registered, GMP-certified facilities
- Generous 90-day guarantee — risk-free trial
- Consistent users see results in as little as 3 weeks
Cons
- Works best for adults 35+ (younger users may see slower results)
- Must be taken daily for best results
- Individual results can vary based on skin type and lifestyle
DeRose Health Ageless review
Emily Johnson, Seattle, WA — Verified Buyer, Age 47
Source: Trustpilot
“After just three weeks of using DeRose Health Ageless II, my skin is noticeably plumper and the winter dryness is completely gone. Friends keep asking if I had a facial — I’m so much more confident now!”
Michael Torres, Miami, FL — Verified Buyer, Age 39
Source: Facebook
“This supplement did wonders for my hair. It feels thicker, stronger, and my nails no longer snap. I didn’t expect such big changes from one capsule a day.”
Priya Sharma, London, UK — Verified Buyer, Age 52
Source: Quora
“Pairing DeRose Health Ageless II with their hair serum has made my skin feel like it’s gotten a new lease on life from within. I've tried many products over the years, but this delivered visible results.”
Jacob Lee, Toronto, Canada — Verified Buyer, Age 45
Source: Reddit
“Skeptical at first, but my skin is smoother and far less irritated after just a month. The fact that it’s clean-label is a huge plus for my sensitive skin.”
Who Should Use This Supplement?
- Adults 35+ wanting to improve skin hydration, smoothness, and firmness
- People experiencing thinning hair or brittle nails
- Anyone seeking a natural, plant-based beauty solution
- Those with dietary sensitivities to gluten, soy, or GMOs
- Busy individuals who want an easy, one-capsule-a-day routine
- Women and men wanting to enhance topical products with internal nourishment
Usage Guide for Maximum Results
- Take 1 capsule daily with water, preferably with food
- Use consistently for at least 3–6 weeks for visible changes
- Pair with DeRose Health’s Revitalize Hair Serum for accelerated results
- Maintain a healthy skincare routine with SPF and hydration
Frequently Asked Questions
Is it plant-based?
Yes — 100% plant-based, rice-derived phytoceramides in a vegetarian capsule.
When will I see results?
Many notice improvements in 3–6 weeks, with fuller effects by 2–3 months.
Can men use it?
Absolutely — ideal for both men and women.
Where is it made?
In the USA, in FDA-registered, GMP-certified facilities.
Final Thoughts & Call-to-Action
Our in-depth DeRose Health Ageless Review shows why Ageless II is a leader in anti-aging supplementation. With its high phytoceramide dose, biotin, and antioxidant support, it's designed to deliver visible, real results for skin, hair, and nails — naturally and safely.
Backed by a 90-day satisfaction guarantee, you can try it risk-free and see the difference for yourself
References
- Vasquez, S. “DeRose Health Ageless II Reviews – Expert Findings on Anti-Aging Benefits and Safety.” Center for Integrative Longevity, 2024.
https://pathology.wustl.edu/app/uploads/formidable/226/Derose_Reviews_946887.pdf - Ellis, M. “DeRose Health Ageless II Reviews (Expert Report) – Anti-Aging Results and Side Effects.” Vital Longevity Clinic, 2025.
https://pathology.wustl.edu/app/uploads/formidable/226/Derose_Reviews_322005.pdf - DeRose Health. “Best Phytoceramide Supplement Under Review: Ageless II.” GlobeNewswire, 2025.
https://www.globenewswire.com/news-release/2025/05/15/3082433/0/en/Best-Phytoceramide-Supplement-Under-Review-Ageless-II-Plant-Derived-Ceramides-by-DeRose.html - Article on aging mechanisms that support the context of supplements like DeRose Ageless: Longo et al. “Gender, aging and longevity in humans: an update of an intriguing model.” PMC, 2016.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4994139/ - Kingfisher Cooperative. “DeRose Health Ageless II Comprehensive Reviews and User Experiences.” 2025.
https://www.kingfishercooperative.com/derose-health-ageless-ii-comprehensive-reviews/ - OUP Academic. “Anti-Aging Research and the Limits of Medicine.” Oxford University Press, 2004.
https://academic.oup.com/book/52830/chapter/421887168 - PubMed. “Evaluation of Anti-aging Agents Using the D-Galactose-Induced Accelerated Aging Model.” 2025.
https://pubmed.ncbi.nlm.nih.gov/40106151/ - Medical News Today. “Emerging Anti-Aging Strategies – Scientific Basis and Efficacy.” 2024.
https://www.academia.edu/61842361/Emerging_Anti_Aging_Strategies_Scientific_Basis_and_Efficacy - Rejuvenation Research. “Commentary on Some Recent Theses Relevant to Combating Aging.” 2015.
https://www.liebertpub.com/doi/10.1089/rej.2015.1792 - Rejuvenation Research. “Commentary on Recent Anti-Aging Theses.” 2020.
https://www.liebertpub.com/doi/full/10.1089/rej.2020.2306
"Dr. Serena Kael is a physician-scientist with an MD-PhD in immunology and public health who focuses on immune system resilience and chronic disease prevention. She has published extensively in medical journals and is the author of Immunity Unlocked: How to Strengthen Your Body’s Natural Defenses. Dr. Kael’s mission is to make complex science accessible to everyone through her writing and speaking engagements. In her free time, she enjoys painting landscapes and volunteering at local health clinics."